\u2022 Identify the key genes involved in the initiation of\u00a0A. tamarense<\/em> blooms, specifically those regulated during the germination of resting cyst life stages;<\/p>\n \u2022 Identify the key genes involved in the development and maintenance of\u00a0A. tamarense<\/em> blooms, specifically those involved in the assimilation of organic and inorganic nutrients, the process of photosynthesis, the production of toxins, and the cell division cycle;<\/p>\n \u2022 Identify the key genes involved in the termination of\u00a0A. tamarense<\/em> blooms, specifically those regulated in response to nutrient limitation, and during the transition from vegetative growth to the sexual cycle that results in resting stage formation;<\/p>\n \u2022 Investigate the physiological state of dinoflagellate cells in situ, by comparing expression profiles of a natural bloom population with the data generated from laboratory cultures. This study is an integrated, collaborative program that relies on expertise in A. tamarense <\/em>molecular evolution, genomics, physiology, ecology, and toxicity. It will produce a valuable molecular resource for scientists working to understand the ecology and toxicity of A. tamarense <\/em>and other HAB species and will provide insights into the unique genome of these fascinating, evolutionarily, and economically important, yet understudied protists.<\/p>\n\nErdner, D.L. and D.M. Anderson. 2006.\u00a0Global transcriptional profiling of the toxic En-Gen: Gene expression and harmful algal bloom dynamics The overall goal of this project is to identify the key cellular processes involved in harmful algal blooms (HABs), commonly called “red tides”. HABs pose a major threat to human health, ecosystem health, and fisheries resources throughout the world. Our model system is the toxic dinoflagellate\u00a0Alexandrium tamarense,…<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":713,"menu_order":13,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/pages\/812"}],"collection":[{"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/comments?post=812"}],"version-history":[{"count":3,"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/pages\/812\/revisions"}],"predecessor-version":[{"id":1531,"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/pages\/812\/revisions\/1531"}],"up":[{"embeddable":true,"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/pages\/713"}],"wp:attachment":[{"href":"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-json\/wp\/v2\/media?parent=812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\ndinoflagellate Alexandrium fundyense using Massively Parallel Signature Sequencing<\/a>.
\nBMC Genomics 7:88 (1-11).\nHackett, J. D., D. Anderson, D. Erdner, and D. Bhattacharya. 2004a.\u00a0Dinoflagellates: A
\nremarkable evolutionary experiment<\/a>. Amer. J. of Botany 91: 1523-1534.\nHackett, J.D., H.S. Yoon, and D. Bhattacharya. 2006. The genomes of dinoflagellates. In:
\nGenome Evolution in Eukaryotic Microbes, (Eds.) L.A. Katz and D. Bhattacharya.
\nOxford University Press.\n\t\t\t\t\n\t\t\t\t![\"(A)](\"https:\/\/www2.whoi.edu\/site\/andersonlab\/wp-content\/uploads\/sites\/20\/2018\/07\/En-gen_77112.jpg\" "\\"En-gen_77112\\"")
\n\t\t\t\t<\/a>\n\t\t(A) Light microscopic image of Alexandrium tamarense. (B) DAPI-stained haploid cell of A. tamarense showing the numerous chromosomes. (D. Bhattacharya, U. Iowa)\n\n","protected":false},"excerpt":{"rendered":"