{"id":747,"date":"2020-03-04T17:43:06","date_gmt":"2020-03-04T21:43:06","guid":{"rendered":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/?page_id=747"},"modified":"2020-06-18T12:49:26","modified_gmt":"2020-06-18T16:49:26","slug":"toxicology-discussions","status":"publish","type":"page","link":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/toxicology-discussions\/","title":{"rendered":"Toxicology Discussions"},"content":{"rendered":"\n\t

Woods Hole Toxicology Roundtable Discussions<\/h1>\n

2017 Tox Roundtable Discussions<\/h2>\n

All presentations will be Fridays, 12-1 in Redfield 2-04 unless noted.<\/p>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Date<\/th>Presenter\/topic<\/th>\n<\/tr>\n<\/thead>\n
7\/12<\/td>Collen Hansel<\/strong> (WHOI, Marine Chemistry) \"Superoxide as it relates to microbial physiology\"<\/td>\n<\/tr>\n
7\/21<\/td>David Lamb<\/strong> (Swansea Medical School) \"Giant viruses and viral cytochromes P450: an enigma wrapped in a mystery\" (VENUE at MBL Bay Paul Center, 12:30pm<\/strong>)<\/td>\n<\/tr>\n
7\/28<\/td>Kirsten Sadler<\/strong> (NYU and MBL) \"Arsenic and ethanol: a potent cocktail that elicits fatty liver disease in zebrafish\"<\/td>\n<\/tr>\n
8\/4<\/td>Keith Cheng<\/strong> (Penn State) [provisional] \"Functional genomics in zebrafish\"<\/td>\n<\/tr>\n
8\/11<\/td>Jennifer Schlezinger<\/strong> (Boston University) \" Bone, an underappreciated target of environmental toxicants\"<\/td>\n<\/tr>\n
8\/18<\/td>Leon Peshkin<\/strong> (Harvard Medical School) \"On the Relationship of Protein and mRNA Dynamics in Vertebrate Embryonic Development\"<\/td>\n<\/tr>\n
8\/25<\/td>Emmy Gordon<\/strong> (Rutgers University) \"Sulfur mustards and ocular effects - recent findings\"<\/td>\n<\/tr>\n
9\/1<\/td>Open<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2016 Toxicology Roundtable Presentations<\/h2>\n

Summer 2016<\/p>\n

All presentations will be Fridays, 12-1 in Redfield 2-04 unless noted.<\/p>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Date<\/th>Presenter\/topic<\/th>\n<\/tr>\n<\/thead>\n
6\/9<\/td>Thiago Parente<\/strong> (Universidade Federal do Rio de Janeiro) \"Diversity of Cytochrome P450 1 (CYP1) genes in Amazonian fishes\"<\/td>\n<\/tr>\n
6\/17<\/td>Donald Stedman<\/strong> (Pfizer) \"What is Pfizer doing with zebrafish: Developmental Screening and more\"<\/td>\n<\/tr>\n
6\/24<\/td>no meeting<\/td>\n<\/tr>\n
7\/1<\/td>Kim Boekelheide<\/strong> (Brown Univ). \"Imaging 3D Human Microtissues to Modernize Toxicity Testing\" To be followed by ice cream!<\/td>\n<\/tr>\n
7\/8<\/td> no meeting<\/td>\n<\/tr>\n
7\/15<\/td>Arielle Woznica<\/strong> (UC Berkeley) \"Bacterial clues, multicellularity, and mating: insights from a choanoflagellate\"<\/td>\n<\/tr>\n
7\/22<\/td>Martin Ronis<\/strong> (LSU Medical School) \u201cDietary N-acetylcysteine and soy protein isolate inhibit progression of fatty liver disease in rodents\u201d<\/td>\n<\/tr>\n
7\/29<\/td>NOAA Hollings Scholars - Ryan Walsh<\/strong> \"Deiodinase 2 expression in killifish: Are there possible PCB effects in fish from New Bedford Harbor?\" and Daniel Chapman<\/strong> \"Phenotypic effects of saxitoxin in zebrafish\"<\/td>\n<\/tr>\n
8\/5<\/td>Jed Goldstone<\/strong> (WHOI) \"Molluscan Cytochrome P450s\" and \"Risk communication on PFOS contamination of drinking water wells in Falmouth\"<\/td>\n<\/tr>\n
8\/12<\/td>no meeting<\/td>\n<\/tr>\n
8\/19<\/td>Michael Gallo<\/strong> (University of Medicine and Dentistry of New Jersey) \"Genetically Engineered Crops: The NAS Committee findings on risks and benefits\"<\/td>\n<\/tr>\n
8\/26<\/td>open<\/td>\n<\/tr>\n
9\/2<\/td>David Lamb<\/strong> (Swansea Medical School Wales) \"Interesting things about novel cytochrome P450s\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2015 Presentations<\/h2>\nSummer 2015
\n2015 Presentations
\nAll presentations will be Fridays, 12-1 in Redfield 2-04 unless noted.\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Date<\/th>Presenter\/topic<\/th>\n<\/tr>\n<\/thead>\n
6\/12<\/td>Matt Salanga<\/strong> (WHOI) CRISPR-Cas9 and gene editing; recent advances and method issues<\/td>\n<\/tr>\n
6\/19<\/td>Jed Goldstone<\/strong> and Neel Aluru<\/strong> (WHOI) Science presented at the 18th Pollutant Responses in Marine Organisms meeting (PRIMO18; in Trondheim May 2015)<\/td>\n<\/tr>\n
6\/26<\/td>John Stegeman<\/strong> (WHOI) Cytochrome P450 20A1 biology and behavioral phenotypes<\/td>\n<\/tr>\n
7\/3<\/td>no seminar<\/strong><\/td>\n<\/tr>\n
7\/10<\/td>Liz Kujawinski<\/strong> (WHOI) Environmental metabolomics<\/td>\n<\/tr>\n
7\/17<\/td>Judy Luborksy<\/strong> (WHOI) The Inflammasome<\/td>\n<\/tr>\n
7\/24<\/td>David Furlow<\/strong> (UC Davis) Thyroid hormone work (HTS), involving the EPA Tox21 group, tadpoles, zebrafish and mouse<\/td>\n<\/tr>\n
7\/31<\/td>Jennifer Schlezinger<\/strong> (BU) Environmental PPARg Agonists: What are they doing to our metabolic and bone health?<\/td>\n<\/tr>\n
8\/7<\/td>no seminar<\/strong><\/td>\n<\/tr>\n
8\/14<\/td>Joanna Wilson<\/strong> (McMaster University) Parental effects of Pharmaceuticals on Zebrafish, emphasizing Carbamazepine and Gemfibrozil<\/td>\n<\/tr>\n
8\/21<\/td>Michale Gallo<\/strong> (Rutgers University\/Robert Wood Johnson Medical) When good chemicals go bad: A history of toxicology<\/td>\n<\/tr>\n
8\/28<\/td>Erica Holland<\/strong> (UC Davis) History and toxicology of ryanodine receptors (ER calcium channels aka the \u201cfoot protein\"); a mechanism of ortho-PCB toxicity
\n
\nfollowed by Annual Roundtable BBQ<\/strong> <\/td>\n<\/tr>\n
9\/11<\/td>Rebecca Helm<\/strong> (WHOI) Tick tock tick tock: Clock mechanisms in Cnidaria<\/td>\n<\/tr>\n
9\/23<\/td>Phillipe Urban<\/strong> (CNRS) Substrate access channels in cytochrome P450 enzymes<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2014 Discussions<\/h2>\n

All presentations will be Fridays, 12-1 in Redfield 2-04 unless noted.<\/p>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Date<\/th><\/th>Presenter\/topic<\/th>\n<\/tr>\n<\/thead>\n

\u00a07\/3<\/p><\/td>

\u00a0<\/p><\/td>

Emma Heart <\/strong>(MBL). \u201cMechanisms of metabolic regulation of insulin \u00a0secretion: \u00a0function and dysfunction.\u201d<\/p><\/td>\n<\/tr>\n

7\/11<\/p><\/td>

\u00a0<\/p><\/td>

Eduardo Rosa-Molinar<\/strong> (MBL and U. of Puerto Rico) \u201cImaging and \u00a0 Identifying Elements of a Fish Spinal Neural Circuit Controlling an Innate \u00a0Behavior\"<\/p><\/td>\n<\/tr>\n

7\/18<\/p><\/td>

\u00a0<\/p><\/td>

Joanna Wilson<\/strong> (McMaster University) \"Multiple stressors in fish\u00a0toxicology\"<\/p><\/td>\n<\/tr>\n

7\/25<\/p><\/td>

\u00a0<\/p><\/td>

Chris Redd<\/strong>y (WHOI) \"Refining current views on the fate of oil in the ocean: Lessons learned from the Deepwater Horizon\"<\/p><\/td>\n<\/tr>\n

8\/1<\/p><\/td>

\u00a0<\/p><\/td>

John Farrington <\/strong>(WHOI)\u00a0 \"The Need for Updated Human Health Risk Assessment for Oil Spill Contaminated Bivalve Seafood: Lessons from the BP-DWH Oil Spill\"<\/td>\n<\/tr>\n

8\/8<\/p><\/td>

\u00a0<\/p><\/td>

Jed Goldstone <\/strong>(WHOI) \"Screening therapies to counteract chlorpyrifos intoxication\"<\/p><\/td>\n<\/tr>\n

8\/15<\/p><\/td>

\u00a0<\/p><\/td>

Nikki Traylor-Knowles<\/strong> (Stanford University)\u00a0 \"Some (do not) Like It Hot: The Role of Tumor Necrosis Factor Receptor In Heat Stressed Corals\"
<\/p><\/td>\n<\/tr>\n

8\/22<\/p><\/td>

\u00a0<\/p><\/td>

Judy Luborsky <\/strong>(Rush Medical and WHOI)\u00a0 \"Ovarian Ovarian cancer in humans and chickens; utility of a non-mammalian model\"
(Followed by BBQ)
<\/strong><\/p><\/td>\n<\/tr>\n

8\/29<\/p><\/td>

\u00a0<\/p><\/td>

Emmy Gordon<\/strong> (Rutgers University and MBL) \"Toxicology of the eye: Changes in provisional matrix after ocular mustard injury\"<\/p><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2013 Presentations<\/h2>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Date<\/th><\/th>Presenter\/topic<\/th>\n<\/tr>\n<\/thead>\n

6\/21<\/p><\/td>

\u00a0<\/p><\/td>

Kat Crawford<\/strong> (BU) \"The public health perspective on remediation of PCB contamination in Boston Harbor\"<\/p><\/td>\n<\/tr>\n

6\/28<\/p><\/td>

\u00a0<\/p><\/td>

Ann Tarrant\u00a0<\/strong>(WHOI) \"Nuclear receptors in early-diverging animal lineages\"<\/p><\/td>\n<\/tr>\n

\u00a07\/5<\/p><\/td>

\u00a0<\/p><\/td>

(no meeting)<\/p><\/td>\n<\/tr>\n

7\/12<\/p><\/td>

\u00a0<\/p><\/td>

Thanos Tzounopolous<\/strong> (Univ. Pittsburg) \"Zinc and synaptic signaling: What is the role of zinc in the nervous system?\"<\/p><\/td>\n<\/tr>\n

7\/19<\/p><\/td>

\u00a0<\/p><\/td>

Laura Vandenberg and Alex Suvorov<\/strong> (UMass Amherst) \"BPA as a model endocrine disruptor: lessons learned in the past 6 years\" and TBA<\/p><\/td>\n<\/tr>\n

7\/26<\/p><\/td>

\u00a0<\/p><\/td>

David Griffith<\/strong> (WHOI) \"Are fish and whales the main source of steroidal estrogens to a sewage-impacted coastal ocean - Massachusetts Bay?\"<\/p><\/td>\n<\/tr>\n

8\/2<\/p><\/td>

\u00a0<\/p><\/td>

Josh Grey<\/strong> (US Coast Guard Academy and MBL) \"Reductive stress and coping mechanisms in the pancreatic beta cell: roles of NQO1 and plasma membrane electron transport (PMET)\"<\/p><\/td>\n<\/tr>\n

8\/9<\/p><\/td>

\u00a0<\/p><\/td>

Jeff Laskin<\/strong> (Rutgers) \"Approaches to treating exposures to highly toxic chemicals\"<\/p><\/td>\n<\/tr>\n

8\/16<\/p><\/td>

\u00a0<\/p><\/td>

Emmy Gordon<\/strong> (Rutgers) \"Alterations in extracellular matrix and matrix metalloproteinases after vesicant injury of the cornea\"<\/p><\/td>\n<\/tr>\n

8\/23<\/p><\/td>

\u00a0<\/p><\/td>

Conor O'Meara<\/strong> (Kalamazoo College&WHOI) \"Studies of pregnane X receptor agonists and target genes in zebrafish\"
Elaine Kuo<\/strong> (Stanford&WHOI) \"Zebrafish DNA methyltransferases and their developmental regulation and induction by TCDD\"
TO BE<\/strong> FOLLOWED BY BBQ
<\/strong><\/p><\/td>\n<\/tr>\n

8\/30<\/p><\/td>

\u00a0<\/p><\/td>

Ben Lemaire?<\/strong> (WHOI) \"Towards the deorphanization of cytochrome P450 20A1 (CYP20A1)\"<\/p><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2011 Round table talks<\/h2>\n

All presentations were Fridays, 12-1 in Redfield 2-04 unless noted.<\/p>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t
\u00a0Date<\/strong><\/th>\u00a0<\/th>\u00a0Presenter\/topic<\/strong><\/th>\n<\/tr>\n<\/thead>\n
6\/30<\/td>\u00a0<\/td>Richard DiGuilio, Duke University
\"Mechanisms of PAH Developmental Toxicity and Evolved Resistance: The Elizabeth River Killifish Story<\/a>\"
NOTE: This is the WHOI Biology Seminar Series at 12 noon (sharp) in Redfield Auditorium<\/strong><\/td>\n<\/tr>\n
\u00a0<\/td>\u00a0<\/td>

<\/td>\n<\/tr>\n
7\/15<\/td>\u00a0<\/td>\u00a0Joshua Grey, USCG Academy
\"Quinone-stimulated insulin secretion \u2013 hydrogen peroxide as a second messenger\"<\/td>\n<\/tr>\n
7\/22<\/td>\u00a0<\/td>\u00a0Martin Ronis, University of Arkansas for Medical Science
\"Wnt b Catenin Signalling is a Common Skeletal Target for both Alcohol and Diet\"<\/td>\n<\/tr>\n
7\/29\u00a0<\/td>\u00a0<\/td>\u00a0<\/td>\n<\/tr>\n
8\/5<\/td>\u00a0<\/td>\u00a0<\/td>\n<\/tr>\n
8\/12<\/td>\u00a0<\/td>\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2010<\/h2>\n\n\n\n\n\t\n\n\t\n\t\n\t
Date<\/th><\/th> Presenter\/topic<\/th>\n<\/tr>\n<\/thead>\n
7\/1
<\/td>		\u00a0<\/td>John Farrington
\"Oil Pollution in the Marine Environment \u2013 An Overview and Lessons Learned from a Research Cruise to the1979 Ixtoc-I Oil Well Blowout, Bay of Campeche,Mexican Waters of the Gulf of Mexico.\"
NOTE: This is the WHOI Biology Seminar Series at 12 noon (sharp) in Redfield Auditorium<\/td>\n<\/tr>\n
7\/9
<\/td>		\u00a0<\/td>Emma Heart
\"The role of NQO1 in beta cell plasma membrane electron transport and insulin secretion\" and discussion on alkylphenols in endocrine disruption
<\/td>\n<\/tr>\n
7\/16
<\/td>		\u00a0<\/td>Phil Gschwend, MIT
\"Organic Contaminants in Sediments: (PAHs,Petroleum Hydrocarbons, PCBs, DDTs...): Getting the 'Bioavailable Dose' right!\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2009<\/h2>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t
\u00a0Date<\/strong><\/th>\u00a0<\/th>\u00a0Presenter\/topic<\/strong><\/th>\n<\/tr>\n<\/thead>\n
10 July

\n\t\t\t<\/td>		\u00a0<\/td>Kimberly Jackson (Spelman College)

\n\t\t\t\"Licorice Constituent and Androgen Receptor Modulation in Prostate Cancer Therapy\"
\t\t<\/td>\n<\/tr>\n
17 July<\/td>\u00a0<\/td>Shanta Messerli (Resident Scientist in the MBL Cellular Dynamics Program)

\n\t\t\tPatrizia Pellegatti (Visiting Researcher from Italy in the Cellular Dynamics Program)

\n\t\t\t\"Sensors of extracellular ATP and applications in cancer detection\" (Candle House 1st Floor)<\/td>\n<\/tr>\n
24 July
\t<\/td>		\u00a0<\/td>Joan Ruderman (Cell Biology, Harvard Medical School)

\n\t\t\t\"Zebrafish embryos:\u00a0 versatile sensors for hormonally active pollutants\"<\/td>\n<\/tr>\n
31 July

\n\t\t\t<\/td>		\u00a0<\/td>Diane Heck (NYMC)

\n\t\t\t\"Catalase function\"
<\/td>\n<\/tr>\n
\u00a0 7 Aug
<\/td>		\u00a0<\/td>No seminar - MBL Corporation meeting
<\/td>\n<\/tr>\n
14 Aug
\t<\/td>		\u00a0<\/td>\u00a0 John Stegeman, Sibel Karchner (WHOI), and Jeff Laskin (Rutgers)

\n\t\t\t\"Aldo-keto reductase (AKR) evolution and function\"<\/td>\n<\/tr>\n
21 Aug
<\/td>		\u00a0<\/td>\u00a0Kim Boekelheide (Brown)

\n\t\t\t\"Endocrine Disruptors and Male Reproductive Health\"

\n\t\t\tTo be held at 11AM in REDFIELD, followed by a cookout.
\t\t<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2008<\/h2>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t
\u00a0Date<\/strong><\/th>\u00a0<\/th>\u00a0Presenter\/topic<\/strong><\/th>\n<\/tr>\n<\/thead>\n
8 July<\/td>\u00a0<\/td>Tom Hutchinson (Plymouth Marine Laboratory)

\n\t\t\tPharmaceuticals and the environment: the human - wildlife connection
\t\t\t<\/td>\n<\/tr>\n
15 July
<\/td>		\u00a0<\/td>David Albertini (Kansas University Medical Center)
\t<\/td>\n<\/tr>\n
22 July
<\/td>		\u00a0<\/td>Mike Gallo (Rutgers)
<\/td>\n<\/tr>\n
29 July
<\/td>		\u00a0<\/td>cancelled - Harlyn Halvorsen memorial service
<\/td>\n<\/tr>\n
5 Aug
<\/td>		\u00a0<\/td>Jed Goldstone (WHOI)

\n\t\t\tEvolution of cytochromes P450 in metazoa
<\/td>\n<\/tr>\n
12 Aug
<\/td>		\u00a0<\/td>\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

2007<\/h2>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t
\u00a0Date<\/th>Presenter\/topic<\/th>\n<\/tr>\n<\/thead>\n
7 Aug<\/td><\/td>\n<\/tr>\n
14 Aug<\/td><\/td>\n<\/tr>\n
21 Aug <\/td>\u00a0Hans Lauffer<\/td>\n<\/tr>\n
28 Aug <\/td>\u00a0John Stegeman<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n","protected":false},"excerpt":{"rendered":"

Woods Hole Toxicology Roundtable Discussions 2017 Tox Roundtable Discussions All presentations will be Fridays, 12-1 in Redfield 2-04 unless noted. 2016 Toxicology Roundtable Presentations Summer 2016 All presentations will be Fridays, 12-1 in Redfield 2-04 unless noted. 2015 Presentations Summer 2015 2015 Presentations All presentations will be Fridays, 12-1 in Redfield 2-04 unless noted. 2014…<\/p>\n","protected":false},"author":83,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/wp-json\/wp\/v2\/pages\/747"}],"collection":[{"href":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/wp-json\/wp\/v2\/users\/83"}],"replies":[{"embeddable":true,"href":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/wp-json\/wp\/v2\/comments?post=747"}],"version-history":[{"count":3,"href":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/wp-json\/wp\/v2\/pages\/747\/revisions"}],"predecessor-version":[{"id":781,"href":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/wp-json\/wp\/v2\/pages\/747\/revisions\/781"}],"wp:attachment":[{"href":"https:\/\/www2.whoi.edu\/site\/stegemanlab\/wp-json\/wp\/v2\/media?parent=747"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}