Understanding Metal Use in Life (Native Metalloproteomics)

Metals are essential micronutrients for all life. These nutritional micronutrients include metals such as iron, zinc, cobalt, nickel, manganese, cadmium and more, where each metal lends its unique chemical properties to proteins or vitamins to create new cellular capabilities. The Saito laboratory develops techniques to learn metal uses in vivo, including metalloproteomic techniques that combine inorganic and organic mass spectrometry methods to localize metals within protein. We also conduct physiological and biochemical characterization of metal use within microbes.

Explore the metalloproteomes of various organisms studied by the Saito Lab in our metallome portal.