From projects funded 2012 - present

Aluru N. Epigenetic effects of environmental chemicals: insights from zebrafish. Curr Opin Toxicol. 2017;6:26-33. Epub 2017/12/05. doi: 10.1016/j.cotox.2017.07.004. PubMed PMID: 29202112; PMCID: PMC5703436.

Aluru N, Deak KL, Jenny MJ, Hahn ME. Developmental exposure to valproic acid alters the expression of microRNAs involved in neurodevelopment in zebrafish. Neurotoxicology and Teratology. 2013;40(0):46-58. doi:; PMCID: 3895482.

Aluru N, Karchner SI, Glazer L. Early Life Exposure to Low Levels of AHR Agonist PCB126 (3,3',4,4',5-Pentachlorobiphenyl) Reprograms Gene Expression in Adult Brain. Toxicol Sci. 2017;160(2):386-97. Epub 2017/10/04. doi: 10.1093/toxsci/kfx192. PubMed PMID: 28973690; PMCID: PMC5837202.

Aluru N, Karchner SI, Krick KS, Zhu W, Liu J. Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB 126). Environ Epigenet. 2018;4(1):dvy005. Epub 2018/04/25. doi: 10.1093/eep/dvy005. PubMed PMID: 29686887; PMCID: PMC5905506.

Aluru N, Kuo E, Helfrich LW, Karchner SI, Linney EA, Pais JE, Franks DG. Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio). Toxicol Appl Pharmacol. 2015;284(2):142-51. Epub 2015/03/04. doi: PubMed PMID: 25732252; PMCID: 4408251.

Anderson D, Keafer B, McGillicuddy D, Solow A, Kleindinst J. Improving the accuracy and utility of harmful algal bloom forecasting systems. The Micropaleontological Society, Special Publications. 2013;5:133-40; PMCID: N/A; Not peer reviewed.

Anderson DM, Couture DA, Kleindinst JL, Keafer BA, McGillicuddy JDJ, Martin JL, Richlen ML, Hickey JM, Solow AR. Understanding interannual, decadal level variability in paralytic shellfish poisoning toxicity in the Gulf of Maine: The HAB Index. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103:264-76. doi:; PMCID: 4058790.

Anderson DM, Keafer BA, Kleindinst JL, McGillicuddy Jr DJ, Martin JL, Norton K, Pilskaln CH, Smith JL, Sherwood CR, Butman B. Alexandrium fundyense cysts in the Gulf of Maine: Long-term time series of abundance and distribution, and linkages to past and future blooms. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103:6-26. doi:; PMCID: 4085992.

Anderson DM, McGillicuddy Jr DJ, DeGrasse SL, Sellner KG, Bricelj VM, Turner JT, Townsend DW, Kleindinst JL. Harmful Algae in the Gulf of Maine: Oceanography, Population Dynamics, and Toxin Transfer in the Food Web. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103:1-376. doi:; PMCID: (edited volume, PMCID not applicable).

Aretxabaleta AL, Butman B, Signell RP, Dalyander PS, Sherwood CR, Sheremet VA, McGillicuddy Jr DJ. Near-bottom circulation and dispersion of sediment containing Alexandrium fundyense cysts in the Gulf of Maine during 2010–2011. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):96-111. doi:; PMCID: 4451834.

Bill BD, Moore SK, Hay LR, Anderson DM, Trainer VL. Effects of temperature and salinity on the growth of Alexandrium (Dinophyceae) isolates from the Salish Sea. Journal of Phycology. 2016;52(2):230-8. doi: 10.1111/jpy.12386; PMCID: 4818979.

Brosnahan ML, Farzan S, Keafer BA, Sosik HM, Olson RJ, Anderson DM. Complexities of bloom dynamics in the toxic dinoflagellate Alexandrium fundyense revealed through DNA measurements by imaging flow cytometry coupled with species-specific rRNA probes. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):185-98. doi:; PMCID: 4039218.

Brosnahan ML, Ralston DK, Fischer AD, Solow AR, Anderson DM. Bloom termination of the toxic dinoflagellate Alexandrium catenella: Vertical migration behavior, sediment infiltration, and benthic cyst yield. Limnology and Oceanography. 2017;62(6):2829-49. doi: 10.1002/lno.10664; PMCID: PMC5725721.

Brosnahan ML, Velo-Suárez L, Ralston DK, Fox SE, Sehein TR, Shalapyonok A, Sosik HM, Olson RJ, Anderson DM. Rapid growth and concerted sexual transitions by a bloom of the harmful dinoflagellate Alexandrium fundyense (Dinophyceae). Limnology and Oceanography. 2015;60(6):2059-78. doi: 10.1002/lno.10155; PMCID: PMC5014212.

Butman B, Aretxabaleta AL, Dickhudt PJ, Dalyander PS, Sherwood CR, Anderson DM, Keafer BA, Signell RP. Investigating the importance of sediment resuspension in Alexandrium fundyense cyst population dynamics in the Gulf of Maine. Deep Sea Res Part 2 Top Stud Oceanogr. 2014;103:79-95. Epub 2014/10/08. doi: 10.1016/j.dsr2.2013.10.011. PubMed PMID: 25288829; PMCID: PMC4185196.

Choi CJ, Brosnahan ML, Sehein TR, Anderson DM, Erdner DL. Insights into the loss factors of phytoplankton blooms: The role of cell mortality in the decline of two inshore Alexandrium blooms. Limnology and Oceanography. 2017;62(4):1742-53. doi: 10.1002/lno.10530. PubMed PMID: WOS:000404993100029.

Deeds JR, Petitpas CM, Shue V, White KD, Keafer BA, McGillicuddy DJ, Jr., Milligan PJ, Anderson DM, Turner JT. PSP toxin levels and plankton community composition and abundance in size-fractionated vertical profiles during spring/summer blooms of the toxic dinoflagellate in the Gulf of Maine and on Georges Bank, 2007, 2008, and 2010: 1. Toxin levels. Deep Sea Res Part 2 Top Stud Oceanogr. 2014;103:329-49. Epub 2014/08/01. doi: 10.1016/j.dsr2.2013.04.013 [doi]. PubMed PMID: 25076816; PMCID: 4112541.

DeGroot DE, Franks DG, Higa T, Tanaka J, Hahn ME, Denison MS. Naturally Occurring Marine Brominated Indoles Are Aryl Hydrocarbon Receptor Ligands/Agonists. Chem Res Toxicol. 2015;28(6):1176-85. Epub 2015/05/23. doi: PubMed PMID: 26001051; PMCID: 4469569.

Feary DA, Burt JA, Bauman AG, Al Hazeem S, Abdel-Moati MA, Al-Khalifa KA, Anderson DM, Amos C, Baker A, Bartholomew A, Bento R, Cavalcante GH, Chen CA, Coles SL, Dab K, Fowler AM, George D, Grandcourt E, Hill R, John DM, Jones DA, Keshavmurthy S, Mahmoud H, Moradi Och Tapeh M, Mostafavi PG, Naser H, Pichon M, Purkis S, Riegl B, Samimi-Namin K, Sheppard C, Vajed Samiei J, Voolstra CR, Wiedenmann J. Critical research needs for identifying future changes in Gulf coral reef ecosystems. Marine Pollution Bulletin. 2013;72(2):406-16. doi:; PMCID: 4118590.

Fernandes LF, Hubbard KA, Richlen ML, Smith J, Bates SS, Ehrman J, Léger C, Mafra Jr LL, Kulis D, Quilliam M, Libera K, McCauley L, Anderson DM. Diversity and toxicity of the diatom Pseudo-nitzschia Peragallo in the Gulf of Maine, Northwestern Atlantic Ocean. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):139-62. doi:; PMCID: 4133141.

Fleming LE, Depledge M, McDonough N, White M, Pahl S, Austen M, Goksoyr A, Solo-Gabriele H, Stegeman J. The Oceans and Human Health Environmenal Science: Oxford Research Encyclopedias 2015. doi: 10.1093/acrefore/9780199389414.013.12.

Ganju NK, Brush MJ, Rashleigh B, Aretxabaleta AL, del Barrio P, Grear JS, Harris LA, Lake SJ, McCardell G, O’Donnell J, Ralston DK, Signell RP, Testa JM, Vaudrey JMP. Progress and Challenges in Coupled Hydrodynamic-Ecological Estuarine Modeling. Estuaries and Coasts. 2015;39(2):311-32. doi: 10.1007/s12237-015-0011-y; PMCID: 5053394.

Glazer L, Hahn ME, Aluru N. Delayed effects of developmental exposure to low levels of the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB126) on adult zebrafish behavior. Neurotoxicology. 2016;52:134-43. Epub 2015/12/01. doi: 10.1016/j.neuro.2015.11.012. PubMed PMID: 26616910; PMCID: PMC4753093.

Glazer L, Wells CN, Drastal M, Odamah KA, Galat RE, Behl M, Levin ED. Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafish. Neurotoxicology. 2018;66:221-32. Epub 2017/09/25. doi: 10.1016/j.neuro.2017.09.007. PubMed PMID: 28935585; PMCID: PMC5858967.

Gomez F, Richlen ML, Anderson DM. Molecular characterization and morphology of Cochlodinium strangulatum, the type species of Cochlodinium, and Margalefidinium gen. nov. for C. polykrikoides and allied species (Gymnodiniales, Dinophyceae). Harmful Algae. 2017;63:32-44. Epub 2017/04/04. doi: 10.1016/j.hal.2017.01.008. PubMed PMID: 28366398.

Halliday E, Ralston DK, Gast RJ. Contribution of sand-associated enterococci to dry weather water quality. Environ Sci Technol. 2015;49(1):451-8. Epub 2014/12/06. doi: 10.1021/es504908h [doi]. PubMed PMID: 25479559; PMCID: 4304835.

Hattenrath-Lehmann TK, Smith JL, Wallace RB, Merlo LR, Koch F, Mittelsdorf H, Goleski JA, Anderson DM, Gobler CJ. The effects of elevated CO2 on the growth and toxicity of field populations and cultures of the saxitoxin-producing dinoflagellate, Alexandrium fundyense. Limnology and Oceanography. 2015;60(1):198-214. doi: 10.1002/lno.10012; PMCID: 5055070.

Hubbard KA, Olson CE, Armbrust EV. Molecular characterization of Pseudo-nitzschia community structure and species ecology in a hydrographically complex estuarine system (Puget Sound, Washington, USA). Marine Ecology Progress Series. 2014;507:39-55. doi: 10.3354/meps10820 PMCID: 4882114.

Ishikawa A, Hattori M, Ishii K-I, Kulis DM, Anderson DM, Imai I. In situ dynamics of cyst and vegetative cell populations of the toxic dinoflagellate Alexandrium catenella in Ago Bay, central Japan. Journal of Plankton Research. 2014;36(5):1333-43. doi: 10.1093/plankt/fbu048; PMCID: 4161227.

Jiang H, Kulis DM, Brosnahan ML, Anderson DM. Behavioral and mechanistic characteristics of the predator-prey interaction between the dinoflagellate Dinophysis acuminata and the ciliate Mesodinium rubrum. Harmful Algae. 2018;77:43-54. Epub 2018/07/15. doi: 10.1016/j.hal.2018.06.007. PubMed PMID: 30005801; PMCID: PMC6089243.

John U, W. Litaker, M. Montresor, S. Murray, M.L. Brosnahan, and D.M. Anderson. Proposal to reject the name Gonyaulax catenella (Alexandrium catenella) (Dinophyceae). Taxon. 2014;63(4):932-3. doi:; PMCID: 4268871.

John U, Litaker RW, Montresor M, Murray S, Brosnahan ML, Anderson DM. Formal Revision of the Alexandrium tamarense Species Complex (Dinophyceae) Taxonomy: The Introduction of Five Species with Emphasis on Molecular-based (rDNA) Classification. Protist. 2014;165(6):779-804. doi:; PMCID: 4457362.

Kleindinst JL, Anderson DM, McGillicuddy Jr DJ, Stumpf RP, Fisher KM, Couture DA, Michael Hickey J, Nash C. Categorizing the severity of paralytic shellfish poisoning outbreaks in the Gulf of Maine for forecasting and management. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):277-87. doi:; PMCID: 4112480.

Koch F, Kang Y, Villareal TA, Anderson DM, Gobler CJ. A novel immunofluorescence flow cytometry technique detects the expansion of brown tides caused by Aureoumbra lagunensis to the Caribbean Sea. Appl Environ Microbiol. 2014;80(16):4947-57. Epub 2014/06/08. doi: 10.1128/AEM.00888-14 PubMed PMID: 24907319; PMCID: 4135766.

Lemaire B, Kubota A, O'Meara CM, Lamb DC, Tanguay RL, Goldstone JV, Stegeman JJ. Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders. Toxicol Appl Pharmacol. 2016;296:73-84. Epub 2016/02/09. doi: 10.1016/j.taap.2016.02.001. PubMed PMID: 26853319; PMCID: PMC4807407.

Li Y, He R, Chen K, McGillicuddy DJ. Variational data assimilative modeling of the Gulf of Maine in spring and summer 2010. Journal of Geophysical Research: Oceans. 2015;120(5):3522-41; PMCID: 4883702.

Li Y, He R, McGillicuddy Jr DJ. Seasonal and interannual variability in Gulf of Maine hydrodynamics: 2002–2011. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):210-22. doi:; PMCID: 4451839.

Lin Q, Liang JR, Huang QQ, Luo CS, Anderson DM, Bowler C, Chen CP, Li XS, Gao YH. Differential cellular responses associated with oxidative stress and cell fate decision under nitrate and phosphate limitations in Thalassiosira pseudonana: Comparative proteomics. PLoS One. 2017;12(9):e0184849. Epub 2017/09/15. doi: 10.1371/journal.pone.0184849. PubMed PMID: 28910417; PMCID: PMC5599023.

Luo CS, Liang JR, Lin Q, Li C, Bowler C, Anderson DM, Wang P, Wang XW, Gao YH. Cellular responses associated with ROS production and cell fate decision in early stress response to iron limitation in the diatom Thalassiosira pseudonana. J Proteome Res. 2014;13(12):5510-23. Epub 2014/11/06. doi: 10.1021/pr5004664 [doi]. PubMed PMID: 25372880; PMCID: 4261981.

McGillicuddy Jr DJ, Brosnahan ML, Couture DA, He R, Keafer BA, Manning JP, Martin JL, Pilskaln CH, Townsend DW, Anderson DM. A red tide of Alexandrium fundyense in the Gulf of Maine. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):174-84. doi:; PMCID: 4142651.

McGillicuddy Jr DJ, Townsend DW, Keafer BA, Thomas MA, Anderson DM. Georges Bank: A leaky incubator of Alexandrium fundyense blooms. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):163-73. doi:; PMCID: 4072335.

Moore SK, Bill BD, Hay LR, Emenegger J, Eldred KC, Greengrove CL, Masura JE, Anderson DM. Factors regulating excystment of in Puget Sound, WA, USA. Harmful Algae. 2015;43:103-10. Epub 2015/06/26. doi: 10.1016/j.hal.2015.01.005 [doi]. PubMed PMID: 26109923; PMCID: 4476272.

Pan G, Chen J, Anderson DM. Modified local sands for the mitigation of harmful algal blooms. Harmful Algae. 2011;10(4):381-7. Epub 2011/05/01. doi: 10.1016/j.hal.2011.01.003. PubMed PMID: 28690475; PMCID: PMC5497708.

Petitpas CM, Turner JT, Deeds JR, Keafer BA, McGillicuddy Jr DJ, Milligan PJ, Shue V, White KD, Anderson DM. PSP toxin levels and plankton community composition and abundance in size-fractionated vertical profiles during spring/summer blooms of the toxic dinoflagellate Alexandrium fundyense in the Gulf of Maine and on Georges Bank, 2007, 2008, and 2010: 2. Plankton community composition and abundance. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):350-67. doi:; PMCID: 4519990.

Petitpas CM, Turner JT, Keafer BA, McGillicuddy Jr DJ, Anderson DM. Zooplankton community grazing impact on a toxic bloom of Alexandrium fundyense in the Nauset Marsh System, Cape Cod, Massachusetts, USA. Harmful Algae. 2015;47:42-55. doi:; PMCID: 5055074.

Pilskaln CH, Anderson DM, McGillicuddy DJ, Keafer BA, Hayashi K, Norton K. Spatial and temporal variability of Alexandrium cyst fluxes in the Gulf of Maine: Relationship to seasonal particle export and resuspension. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):40-54. doi:; PMCID: 4243940.

Pilskaln CH, Hayashi K, Keafer BA, Anderson DM, McGillicuddy Jr DJ. Benthic nepheloid layers in the Gulf of Maine and Alexandrium cyst inventories. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):55-65. doi:; PMCID: 4238928.

Ralston DK, Brosnahan ML, Fox SE, Lee KD, Anderson DM. Temperature and residence time controls on an estuarine harmful algal bloom: Modeling hydrodynamics and Alexandrium fundyense in Nauset estuary. Estuaries and Coasts. 2015;38(6):2240-58. doi: 10.1007/s12237-015-9949-z; PMCID: 4675069.

Ralston DK, Keafer BA, Brosnahan ML, Anderson DM. Temperature dependence of an estuarine harmful algal bloom: Resolving interannual variability in bloom dynamics using a degree day approach. Limnol Oceanogr. 2014;59(4):1112-26. Epub 2014/11/25. doi: 10.4319/lo.2014.59.4.1112 [doi]. PubMed PMID: 25419003; PMCID: 4237216.

Richlen ML, Zielinski O, Holinde L, Tillmann U, Cembella A, Lyu Y, Anderson DM. Distribution of Alexandrium fundyense (Dinophyceae) cysts in Greenland and Iceland, with an emphasis on viability and growth in the Arctic. Marine Ecology Progress Series. 2016;547:33-46; PMCID: 788393.

Richlen ML, Zielinski O, Holinde L, Tillmann U, Cembella A, Lyu Y, Anderson DM. Distribution of Alexandrium fundyense (Dinophyceae) cysts in Greenland and Iceland, with an emphasis on viability and growth in the Arctic. Mar Ecol Prog Ser. 2016;547:33-46. Epub 2016/10/11. doi: 10.3354/meps11660. PubMed PMID: 27721528; PMCID: PMC5055058.

Roncalli V, Turner JT, Kulis D, Anderson DM, Lenz PH. The effect of the toxic dinoflagellate Alexandrium fundyense on the fitness of the calanoid copepod Calanus finmarchicus. Harmful Algae. 2016;51:56-66; PMCID: 5051577.

Sehein T, Richlen ML, Nagai S, Yasuike M, Nakamura Y, Anderson DM. Characterization of 17 new microsatellite markers for the dinoflagellate Alexandrium fundyense (Dinophyceae), a harmful algal bloom species. Journal of Applied Phycology. 2016;3:1677-81. doi: 10.1007/s10811-015-0681-7; PMCID: 4890638

Smith J, Gellene AG, Hubbard KA, Bowers HA, Kudela RM, Hayashi K, Caron DA. Pseudo-nitzschia species composition varies concurrently with domoic acid concentrations during two different bloom events in the Southern California Bight. Journal of Plankton Research. 2018;40(1):29-45. doi: 10.1093/plankt/fbx069. PubMed PMID: WOS:000423304300004.

Smith JL, Tong M, Kulis D, Anderson DM. Effect of ciliate strain, size, and nutritional content on the growth and toxicity of mixotrophic Dinophysis acuminata. Harmful Algae. 2018;78:95-105. Epub 2018/09/11. doi: 10.1016/j.hal.2018.08.001. PubMed PMID: 30196930.

Stegeman JJ, Behrendt L, Woodin BR, Kubota A, Lemaire B, Pompon D, Goldstone JV, Urban P. Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast. Biochim Biophys Acta. 2015;1850(11):2340-52. Epub 2015/08/02. doi: 10.1016/j.bbagen.2015.07.010. PubMed PMID: 26231923; PMCID: PMC4587093.

Tong M, Smith JL, Kulis DM, Anderson DM. Role of dissolved nitrate and phosphate in isolates of Mesodinium rubrum and toxin-producing Dinophysis acuminata. Aquatic Microbial Ecology. 2015;75(2):169-85. doi: 10.3354/ame01757 PMCID: 5055077.

Tong M, Smith JL, Richlen M, Steidinger KA, Kulis DM, Fux E, Anderson DM. Characterization and comparison of toxin-producing isolates of Dinophysis acuminata from New England and Canada. Journal of Phycology. 2015;51(1):66-81. doi: 10.1111/jpy.12251; PMCID: PMC5428078.

Townsend DW, McGillicuddy Jr DJ, Thomas MA, Rebuck ND. Nutrients and water masses in the Gulf of Maine–Georges Bank region: Variability and importance to blooms of the toxic dinoflagellate Alexandrium fundyense. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):238-63. doi:; PMCID: 4448144.

Townsend DW, Pettigrew NR, Thomas MA, Neary MG, McGillicuddy D, J, O'Donnell J. Water masses and nutrient sources to the Gulf of Maine. Journal of Marine Research. 2015;73(3-4):93-122; PMCID: 5051723.

Vahtera E, Crespo BG, McGillicuddy Jr DJ, Olli K, Anderson DM. Alexandrium fundyense cyst viability and germling survival in light vs. dark at a constant low temperature. Deep Sea Research Part II: Topical Studies in Oceanography. 2014;103(0):112-9. doi:; PMCID: 4112483.

Velo-Suarez L, Brosnahan ML, Anderson DM, McGillicuddy Jr DJ. A quantitative assessment of the role of the parasite Amoebophrya in the termination of Alexandrium fundyense blooms within a small coastal embayment. PloS one. 2013;8(12):e81150. doi:; PMCID: 3852033.

Wang L, Zhang J, Duan J, Gao X, Zhu W, Lu X, Yang L, Zhang J, Li G, Ci W, Li W, Zhou Q, Aluru N, Tang F, He C, Huang X, Liu J. Programming and Inheritance of Parental DNA Methylomes in Mammals. Cell. 2014;157(4):979-91. doi:; PMCID: 4096154.

Wells ML, Trainer VL, Smayda TJ, Karlson BSO, Trick CG, Kudela RM, Ishikawa A, Bernard S, Wulff A, Anderson DM, Cochlan WP. Harmful algal blooms and climate change: Learning from the past and present to forecast the future. Harmful Algae. 2015;49:68-93. doi:; PMCID: 4800334.

Zhou J, Lyu Y, Richlen M, Anderson DM, Cai Z. Quorum sensing is a language of chemical signals and plays an ecological role in algal-bacterial interactions. CRC Crit Rev Plant Sci. 2016;35(2):81-105. Epub 2016/01/01. doi: 10.1080/07352689.2016.1172461. PubMed PMID: 28966438; PMCID: PMC5619252.