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Projects

Adaptation to Pollutants:

PCB-Resistant Fish

The goal of this research is to understand the genetic mechanisms of evolved resistance to toxic chemicals in fish living in highly contaminated sites.

 

 

 

Oceans and Human Health:

Harmful Algal Bloom (HAB) Toxins

In this project we are investigating the neurodevelopmental toxicity of harmful algal bloom toxins such as domoic acid (DA) and saxitoxin (STX).

 

 

Marine Microplastics and Nanoplastics

Several projects address the fate and impacts of microplastics and nanoplastics in the marine environment.

Aryl Hydrocarbon Receptor Biology

We are studying the diversity and evolution of AHR, a protein involved in the mechanism of toxicity of a variety of synthetic and natural compounds.

 

Marine Natural Products

We are investigating the biological activity, including possible toxicity, of halogenated marine natural products.

 

 

Mechanisms of Embryo Response to Oxidative Stress

The goal of this research is to to elucidate the mechanisms by which vertebrate embryos respond to oxidative stress during development. We use zebrafish as a model system.

Gene-Environment Interactions

in Congenital Heart Disease

We are using the Atlantic killifish population-based model system to elucidate the interaction of genetic variation and environmental exposures in the etiology of congenital heart disease.